The rules of 75 are simple: prank call a random person and scare the hell out of them for 75 seconds. If the person laughs or hangs up, you lose. Whoever has the best scare wins. The spring semester is coming to a close at a prestigious private university in Colorado. A close-knit circle of friends who have dubbed themselves the Crew, are tired of studying for finals and engage in a harmless prank calling contest called 75. For the Crew and their friends, 75 quickly becomes a popular game on campus. When a rich classmate invites the Crew to his familys hideaway mansion in the mountains, they begin to play an exclusive round of 75. It soon turns into an intense game of survival when someone accidentally calls the wrong person. As the body count continues to rise, those who remain attempt everything imaginable to escape the isolated mansion. Meanwhile a detective (Rutger Hauer) has noticed a disturbing connection between a series of brutal axe murders ten years ago and more recent crimes. It appears that members of the Crew are the survivors of a childhood game of '75' that went horribly wrong. He sets out for the mansion not knowing that history has repeated itself.